Riyadh saudi zip code8/29/2023 ![]() ![]() In the airway tissues of asthmatics, improvement of the inflammatory state results, at least in part, from the glucocorticoid-induced apoptosis of infiltrated pro-inflammatory cells of lymphoid (e.g., T lymphocytes, NK cells) and myeloid (e.g., eosinophils, macrophages) lineages.Ī common characteristic of asthmatic patients is airway tissue remodelling, that seemingly result from attempted healing processes by injured tissue after chronic exposure to environmental irritants. Despite the risks of side effects, glucocorticoids remain up-to-date the most widely prescribed and effective agents for the treatment of chronic inflammation of the airways such as asthma and COPD. Naturally occurring glucocorticoids (e.g., cortisol) and their synthetic derivatives (e.g., dexamethasone) are a class of powerful anti-inflammatory steroid molecules in use since several decades to keep inflammatory processes under control.
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